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“Will it serve as a useful resource for clinicians who encounter patients with PTSD and comorbid MTB-PTSD? Yes. I came away learning a few important bits of information, which I anticipate will impact both my clinical and forensic practice. For that reason alone, I benefitted from reading this text. I expect examinees and referrals sources will also benefit from my having acquired this additional knowledge. In that respect, reading this book was 'win-win' (with no downside) for all concerned.”

—The Clinical Neuropsychologist


“Assessment, treatment, and the costs of delivering care are summarized in a pragmatic and comprehensive manner. This volume is a timely, compact, and remarkably current resource for those who deal with such patients, providing the bases for knowledgeable decisions about how to proceed.”

—Quarterly Review of Biology


“Many of the most active and respected researchers in the fields of mTBI and PTSD explain the current state of knowledge and explore the known issues. These include researchers long considered experts in the field, such as the editors of the volume, Jennifer Vasterling, Richard Bryant, and Terence Keane, as well as researchers more recently making significant contributions, including Mark Gilbertson, Erin Bigler, and Lisa Najavits. This volume takes a comprehensive approach to understanding the relationship between PTSD and mTBI, examining their impact on psychological and behavioral symptoms, cognitive functioning, brain structure and function, assessment, and treatment....Provid[es] a comprehensive overview of the state of the science as it applies to PTSD and mTBI in a logical and useful manner with surprising success, given the complexities and uncertainties that currently exist in the field. Students and individuals new to the fields will certainly benefit from the vast amount of information condensed into a single volume. Providers already working in the field will also benefit from the integration and interpretation of the most recent research into a text that is easy to read and reference. Chapters are written in an easy-to-follow style without reliance on jargon, rendering a text that is approachable, yet appropriately detailed and informative for the practicing psychologist to benefit from as well....A well-written and well-edited text that is destined to find a home on the bookshelves of many psychologists, no matter their area of expertise.”

—PsycCRITIQUES


“The editors assembled an impressive array of contributors and created a comprehensive volume....This is an outstanding volume, the content of which is essential for any provider to understand when addressing either of these conditions alone or in combination....A major contribution to the field, pulling together disparate resources and presenting them in a manner that is immediately usable by a wide range of practitioners. It will certainly help neuropsychologists navigate these difficult symptom presentations as they conduct assessments of these individuals. The volume is geared to provide valuable information to providers throughout the entire spectrum of care, from acute management and early intervention, to informed assessment practices, and finally to longer term empirically validated treatments. This volume may easily be considered one of the key resources on PTSD and mTBI/concussion at this time.”

—Archives of Clinical Neuropsychology


“The book is well laid out and well written. The volume brings together science and practice and is accessible to readers who are taking a first foray into understanding the complicated intersection of PTSD and mTBI. Those well versed in this literature will appreciate the complexity of issues that is presented. This book will assist emergency room doctors, experienced clinicians, as well as graduate students with case conceptualization and assessment and treatment planning. The editors provide a solid framework for conceptualizing the relevance of mTBI and PTSD in both civilian and military populations. A strength of this book is that the editors’ definitions are consistently adopted by the authors of the different chapters, and the issues that are initially raised are expounded on in subsequent chapters. Those who read the book cover to cover will appreciate that the editors ensured consistency across chapters while fastidiously avoiding redundancy….Overall the text is excellent and we appreciated that cultural considerations were addressed….We highly recommend this book to clinicians who want to learn more about these important issues.”

—Journal of Trauma & Dissociation


“Clinicians and scientists alike are certain to welcome this volume, which meets a real need in presenting a comprehensive review of the basic and clinical science of PTSD and mTBI. The biopsychosocial conceptual framework provides a perfect translational bridge to evidence-based clinical management. The book will rapidly become the reference of choice for clinicians facing the complexities of these two conditions and for students in the neurosciences.”

—Michael McCrea, PhD, ABPP, Professor and Director of Brain Injury Research, Departments of Neurosurgery and Neurology, Medical College of Wisconsin


“Vasterling, Bryant, and Keane have assembled an outstanding group of experts to provide a conceptual, scientific, and clinical overview of this daunting challenge. Co-occurring PTSD and mTBI unfortunately has emerged as a common problem for many service members and veterans in recent years. Since PTSD and mTBI affect each other, it is imperative that clinicians treat them concurrently, and do so within a multidisciplinary context. This book provides a thoughtful, comprehensive review of what we know, what we don’t know, and what we need to do to fill in the blanks. It should be mandatory reading for anyone in the field.”

—Matthew J. Friedman, MD, PhD, Senior Advisor, National Center for PTSD, U.S. Department of Veterans Affairs; Professor of Psychiatry and Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth


“This one-of-a-kind book from prominent international experts provides a scholarly and practical synthesis of the complex interaction between PTSD and mTBI. Clearly written chapters provide state-of-the-art information and clinical guidance on assessment and management in both civilian and military settings. Practitioners, researchers, educators, and trainees (students and residents) in the fields of mental health, neurology, and rehabilitation medicine all will benefit greatly from reading this book and having it as an essential reference on their bookshelves.”

—Jesse R. Fann, MD, MPH, Departments of Psychiatry and Behavioral Sciences, Rehabilitation Medicine, and Epidemiology, University of Washington


“The association between PTSD and mTBI is a vexing problem. This volume provides much-needed clarification and direction for clinicians and researchers alike. It brings together leading authorities who provide critical insights, making it an invaluable resource. The book has particular relevance for those treating service members and veterans.”

—Alexander C. McFarlane, MD, Director, Center for Traumatic Stress Studies, University of Adelaide, Australia

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Table of Contents

I. Introduction

1. Understanding the Interface of Traumatic Stress and Mild Traumatic Brain Injury: Background and Conceptual Framework, Jennifer J. Vasterling, Richard A. Bryant, and Terence M. Keane

II. Clinical Presentations and Mechanisms

2. Understanding Mild Traumatic Brain Injury: Neuropathology and Neuroimaging, Erin D. Bigler and William L. Maxwell

3. A Biopsychosocial Conceptualization of Poor Outcome from Mild Traumatic Brain Injury, Grant L. Iverson

4. Understanding Posttraumatic Stress Disorder: Implications for Comorbid Posttraumatic Stress Disorder and Mild Traumatic Brain Injury, Jasmeet Pannu Hayes and Mark W. Gilbertson

5. Effects of Traumatic Brain Injury–Associated Neurocognitive Alterations on Posttraumatic Stress Disorder, Mieke Verfaellie, Melissa M. Amick, and Jennifer J. Vasterling

III. Commonly Associated Conditions

6. Chronic Pain, John D. Otis, Catherine B. Fortier, and Terence M. Keane

7. Substance Use Disorder, Lisa M. Najavits, Jennifer Highley, Sara L. Dolan, and Frank A. Fee

IV. Clinical Management

8. Assessment, Erin W. Ulloa, Brian P. Marx, Rodney D. Vanderploeg, and Jennifer J. Vasterling

9. Assessment in Contexts That Threaten Response Validity, Jon D. Elhai, Jerry J. Sweet, Leslie M. Guidotti Breting, and Danny Kaloupek

10. Treatment of Mild Traumatic Brain Injury, Jennie Ponsford

11. Treatment of Posttraumatic Stress Disorder Following Mild Traumatic Brain Injury, Richard A. Bryant and Brett T. Litz

12. Implications for Service Delivery in the Military, Richard A. Bryant, Carl A. Castro, and Grant L. Iverson

13. Estimating the Costs of Care, Ann Hendricks, Maxine Krengel, Katherine M. Iverson, Rachel Kimerling, Carlos Tun, Jomana Amara, and Henry L. Lew

V. Conclusions

14. Understanding the Interface of Traumatic Stress and Mild Traumatic Brain Injury: Future Directions in Science and Clinical Practice, Jennifer J. Vasterling, Richard A. Bryant, and Terence M. Keane

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About the Editors

Jennifer J. Vasterling, PhD, is Chief of Psychology at the VA Boston Healthcare System. She is also a clinical neuropsychologist, an active researcher in the VA National Center for PTSD, and Professor of Psychiatry at Boston University School of Medicine. Dr. Vasterling is a recipient of the Award for Outstanding Contributions to the Science of Trauma Psychology from the American Psychological Association (Division 56, Division of Trauma Psychology). She is an authority on the neuropsychological features of PTSD and is known for her work examining the cognitive and emotional changes that accompany war-zone deployment.

• All titles by Jennifer J. Vasterling

Richard A. Bryant, PhD, is Scientia Professor of Psychology at the University of New South Wales. He is also an Australian Research Council Laureate Fellow and Director of the Traumatic Stress Clinic at Westmead Hospital in Sydney. Dr. Bryant is a recipient of honors including the Distinguished Contribution to Psychological Science Award from the Australian Psychological Society and the Robert S. Laufer Award for Outstanding Scientific Achievement from the International Society for Traumatic Stress Studies (ISTSS). His work focuses on the intersection of PTSD and traumatic brain injury, the assessment and treatment of acute trauma reactions, and the cognitive and biological mechanisms underpinning traumatic stress.

• All titles by Richard A. Bryant

Terence M. Keane, PhD, is Director and Associate Chief of Staff for Research and Development at the VA National Center for PTSD, Behavioral Sciences Division, VA Boston Healthcare System. He is also Assistant Dean for Research and Professor and Vice-Chairman of Psychiatry at Boston University School of Medicine. Dr. Keane is a recipient of the Lifetime Achievement Award from the ISTSS, among numerous other awards. He developed many of the most widely used PTSD assessment measures and is an authority on the cognitive-behavioral treatment of PTSD.

• All titles by Terence M. Keane

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Contributors

Jomana Amara, PhD, Defense Resource Management Institute, Naval Postgraduate School, Monterey, California

Melissa M. Amick, PhD, Defense and Veterans Brain Injury Center, VA Boston Healthcare System, Boston, Massachusetts

Erin D. Bigler, PhD, Department of Psychology and Neuroscience Center, Brigham Young University, Provo, Utah

Leslie M. Guidotti Breting, PhD, Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois

Richard A. Bryant, PhD, School of Psychology, University of New South Wales, Sydney, Australia

Carl A. Castro, PhD, United States Army Medical Research and Materiel Command, Fort Detrick, Frederick, Maryland

Sara L. Dolan, PhD, Department of Psychology and Neuroscience, Baylor University, Waco, Texas

Jon D. Elhai, PhD, Department of Psychology, University of Toledo, Toledo, Ohio

Frank A. Fee, PhD, private practice, Houston, Texas

Catherine B. Fortier, PhD, VA Boston Healthcare System; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts

Mark W. Gilbertson, PhD, Manchester VA Medical Center, Manchester, New Hampshire; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Jasmeet Pannu Hayes, PhD, National Center for PTSD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Ann Hendricks, PhD, Health Care Financing and Economics, VA Boston Healthcare System; Department of Health Policy and Management, Boston University School of Public Health, Boston, Massachusetts

Jennifer Highley, NP, Department of Behavioral Health, USA MEDDAC, West Point, New York; Columbia University School of Nursing, New York, New York

Grant L. Iverson, PhD, Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada, and Defense and Veterans Brain Injury Center, Walter Reed Army Medical Center, Washington, DC

Katherine M. Iverson, PhD, National Center for PTSD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Danny Kaloupek, PhD, National Center for PTSD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Terence M. Keane, PhD, VA Boston Healthcare System; Department of Psychiatry and Department of Psychology, Boston University, Boston, Massachusetts

Rachel Kimerling, PhD, National Center for PTSD and Center for Health Care Evaluations, Washington, DC; VA Palo Alto Healthcare System, Palo Alto, California

Maxine Krengel, PhD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Henry L. Lew, MD, PhD, Defense and Veterans Brain Injury Center, Department of Defense, Richmond, Virginia; University of Hawaii at Manoa, Honolulu, Hawaii

Brett T. Litz, PhD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Brian P. Marx, PhD, VA National Center for PTSD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

William L. Maxwell, PhD, Department of Anatomy, University of Glasgow, Glasgow, Scotland

Lisa M. Najavits, PhD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

John D. Otis, VA Boston Healthcare System; Department of Psychiatry and Department of Psychology, Boston University, Boston, Massachusetts

Jennie Ponsford, PhD, MAPsS, School of Psychology and Psychiatry, Monash University; Monash–Epworth Rehabilitation Research Centre, Epworth Hospital; National Trauma Research Institute, Alfred Hospital, Melbourne, Australia

Jerry J. Sweet, PhD, Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neuroscience, Pritzker School of Medicine, University of Chicago, Chicago, Illinois

Carlos Tun, MD, Physical Medicine and Rehabilitation Service, VA Boston Healthcare System; Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts

Erin W. Ulloa, PhD, Behavioral Health Lab, Philadelphia VA Medical Center, Philadelphia, Pennsylvania

Rodney D. Vanderploeg, PhD, ABPP-CN, Department of Mental Health and Behavioral Sciences, HSR&D/RR&D Center of Excellence: Maximizing Rehabilitation Outcomes, and Defense and Veterans Brain Injury Center, James A. Haley Veterans Hospital; Department of Psychiatry and Neurosciences, and Department of Psychology, University South Florida, Tampa, Florida

Jennifer J. Vasterling, PhD, Psychology Service and VA National Center for PTSD, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Mieke Verfaellie, PhD, Memory Disorders Research Center, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

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Audience

Mental health practitioners and trauma specialists, including neuropsychologists, clinical psychologists, psychiatrists, and social workers.

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Course Use

May serve as a supplemental text in graduate-level courses.