Treatment of Bipolar Disorder in Children and Adolescents

Edited by Barbara Geller and Melissa P. DelBello

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Hardcover
April 28, 2008
ISBN 9781593856786
Price: $61.00
418 Pages
Size: 6" x 9"
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418 Pages
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Recent advances in evidence-based treatment of pediatric bipolar disorder are comprehensively reviewed in this authoritative volume. The prominent editors and contributors examine the current status of widely used medications and psychosocial therapies, and explore new horizons in tailoring treatment to individuals' neurobiological and clinical profiles. Chapters on specific populations discuss strategies for addressing common co-occurring disorders in children and adolescents with bipolar disorder, treating preschoolers, targeting depressive symptoms, and improving early intervention and prevention. Other essential topics include medication side effects and approaches to monitoring and ameliorating them, and ethical issues related to treatment and research.

“This book is recommended for advanced clinicians including pediatric physicians, psychiatrists, psychologists and researchers, or anyone who provides treatment to the child and adolescent population....This book provides an overview of current research on bipolar disorder and its treatment for adolescents.”

Psychiatric Rehabilitation Journal


“Dr. Barbara Geller and Dr. Melissa P. DelBello have edited a timely volume drawing on their expertise....Both of these women are respected leading clinical researchers who have edited an authoritative volume that examines the current status of medications and psychosocial therapy for children and adolescents diagnosed with bipolar disorder. These authors have highlighted the key questions and the controversy our field faces. They have brought together an outstanding group of leading experts who have reviewed and critiqued the most significant studies in child and adolescent psychiatry with regard to bipolar disorder....This book is an invaluable resource for clinicians and researchers who work with children and adolescents.”

Bulletin of the Menninger Clinic


“A comprehensive volume on a topic of great importance....Given the rate at which the wave of PBD diagnosis has been rising across the broad swath of clinical settings, the tools in this care package will be a welcome addition to the kit of practitioners from multiple disciplines. As the first book focused solely on the treatment of bipolar disorder in young people, Treatment of Bipolar Disorder in Children and Adolescents sets the bar high for future books on the topic, with wide inclusion of treatment types and broad readership appeal.”

PsycCRITIQUES


“This is a high quality, densely informative book on bipolar in children and adolescents. It is full of useful and resourceful information presented in a concise and easy to read manner. I strongly recommend this book to anyone involved in the treatment of children and adolescents with bipolar disorder....4 stars!”

Doody's Review Service


“The good news is that the knowledge base for treating bipolar disorder in youth has grown. The bad news: keeping up with the state of the science may be difficult. But the best news is the publication of this volume, which compiles the most comprehensive and up-to-date information about evidence-based treatments, as well as other relevant research. The contributors are key people who have been instrumental in the advances they describe. This is an important book for clinicians and researchers alike.”

—Gabrielle A. Carlson, MD, Director, Child and Adolescent Psychiatry, Stony Brook University School of Medicine


“This exemplary book, full of rich, age-specific treatment information, is an amazing reflection of the growth in knowledge on treatment of children and adolescents with bipolar disorder. The editors are to be commended for the quality of the individual chapters, which are written by clinician-researchers who are the leaders in their respective areas and who present a very balanced view of the treatment of this complex disorder. The book highlights exciting advances in such areas as matching treatment to individuals and integrating psychopharmacological and psychosocial interventions. An invaluable resource for clinicians and researchers.”

—Graham Emslie, MD, Charles E. Seay and Sarah M. Seay Chair in Child Psychiatry, University of Texas Southwestern Medical Center at Dallas


“This timely book reflects a range of recent developments in the field. Unique features include the discussions of metabolic considerations; recent advances in pharmacological treatments; and chapters on preschool presentation, early intervention, and ethics, which present important perspectives on complex issues. Readers will be pleasantly impressed with the progress and consensus charted in this book.”

—Eric A. Youngstrom, PhD, Professor of Psychology and Neuroscience, University of North Carolina at Chapel Hill

Table of Contents

1. Introduction, Melissa P. DelBello and Barbara Geller

I. Diagnosis and Treatments

2. Diagnosis, Prognosis, and Personalized Medicine, Rebecca Tillman and Barbara Geller

3. Neuropsychopharmacology, Nick C. Patel and Melissa P. DelBello

4. Lithium, Robert L. Findling and Mani N. Pavuluri

5. Atypical Antipsychotics in the Treatment of Early-Onset Bipolar Disorder, Jean A. Frazier, Hallie Bregman, and Joseph A. Jackson

6. Mood Stabilizers, Robert A. Kowatch

7. Newer Drugs, Adelaide S. Robb and Paramjit T. Joshi

8. Nonpharmacological Biological Treatment for Pediatric Bipolar Disorder: Omega-3 Fatty Acids and Complementary and Alternative Medicine

Russell E. Scheffer

9. Family-Focused Treatment for Bipolar Disorder in Adolescence, David J. Miklowitz, Kimberley L. Mullen, and Kiki D. Chang

10. Psychoeducational Psychotherapy, Kristen H. Davidson and Mary A. Fristad

II. Comorbid Disorders and Special Populations

11. Pharmacotherapy for Attention-Deficit/Hyperactivity Disorder in Children with Mania, Karen Dineen Wagner

12. Pediatric Bipolar Disorder and Substance Use Disorders: The Nature of the Relationship, Subtypes at Risk, and Treatment Issues, Timothy E. Wilens and Martin Gignac

13. Pediatric Bipolar Disorder and Comorbid Conditions: Treatment Implications, Gagan Joshi and Janet Wozniak

14. Treatment of Preschool Bipolar Disorder: A Novel Parent–Child Interaction Therapy and Review of Data on Psychopharmacology, Joan L. Luby, Melissa Meade Stalets, Samantha Blankenship, Jennifer Pautsch, and Molly McGrath

15. Treatment of Children and Adolescents at High Risk for Bipolar Disorder, Kiki D. Chang

16. Treatment of Bipolar Depression, Shannon Rae Barnett, Mark A. Riddle, and John T. Walkup

III. Other Issues

17. Polycystic Ovary Syndrome, Paramjit T. Joshi and Adelaide S. Robb

18. Weight Gain and Metabolic Abnormalities in Pediatric Bipolar Disorder, Christoph U. Correll

19. Ethical and Regulatory Aspects in the Treatment of Children and Adolescents with Bipolar Disorder, Benedetto Vitiello


About the Editors

Barbara Geller, MD, is Professor of Psychiatry at Washington University in St. Louis. An internationally recognized researcher for studies of child and adolescent bipolar disorders, Dr. Geller is principal investigator on multiple National Institute of Mental Health-funded projects. Dr. Geller earned her medical degree from Albert Einstein College of Medicine in New York, and completed her residency and fellowship at New York University-Bellevue Medical Center. She has served on numerous federal advisory committees, editorial boards, and advocacy group scientific advisory boards. Among her awards are the American Academy of Child and Adolescent Psychiatry Nathan Cummings Special Research Award and the National Alliance on Mental Illness Exemplary Psychiatrist Award. Widely published, Dr. Geller has written more than 125 articles on diagnostic characteristics, phenomenology, longitudinal course, family psychopathology, molecular genetics, and pharmacological treatment of pediatric manic-depressive disorders.

Melissa P. DelBello, MD, MS, is Associate Professor of Psychiatry and Pediatrics, Vice-Chair for Clinical Research, and Codirector of the Division of Bipolar Disorders Research at the University of Cincinnati College of Medicine. She is also Director, Research Education and Training, Child and Adolescent Psychiatry Division, at Cincinnati Children’s Hospital Medical Center. Dr. DelBello earned her medical degree with honors from the University of Rochester School of Medicine in Rochester, New York. She completed her residency in psychiatry at the Payne Whitney Clinic, New York Hospital-Cornell Medical Center, and at the University of Cincinnati College of Medicine, and a fellowship in Child and Adolescent Psychiatry at Cincinnati Children’s Hospital Medical Center. Dr. DelBello is the author or coauthor of over 100 journal articles or chapters, and her primary research interests include neuropharmacology and neurodevelopment of pediatric bipolar disorder.

Contributors

Shannon Rae Barnett, MD, is Assistant Professor of Psychiatry in the Division of Child and Adolescent Psychiatry at the Johns Hopkins University School of Medicine, Baltimore, Maryland.

Samantha Blankenship, MSW, is the study monitor for the Treatment of Early Age Mania Study at Washington University School of Medicine in St. Louis, St. Louis, Missouri.

Hallie Bregman, BA, is a research coordinator at the Child and Adolescent Neuropsychiatric Research Program at Cambridge Health Alliance, Cambridge, Massachusetts.

Kiki D. Chang, MD, is Associate Professor of Psychiatry and Behavioral Sciences at the Stanford University School of Medicine, Division of Child Psychiatry, Stanford, California.

Christoph U. Correll, MD, is Assistant Professor of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York.

Kristen H. Davidson, PhD, is in private practice in Rochester, New York, and is a clinical senior instructor in the Departments of Psychiatry and Pediatrics at the University of Rochester Medical Center, Rochester, New York.

Melissa P. DelBello, MD, MS, is Associate Professor of Psychiatry and Pediatrics, Vice-Chair for Clinical Research, and Codirector, Division of Bipolar Disorders Research at the University of Cincinnati College of Medicine, and Director, Research Education and Training, Child and Adolescent Psychiatry Division, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Robert L. Findling, MD, is Director of the Division of Child and Adolescent Psychiatry at University Hospitals Case Medical Center and Professor of Psychiatry and Pediatrics at Case Western Reserve University, Cleveland, Ohio.

Jean A. Frazier, MD, is Director of Child Psychopharmacology and the Child and Adolescent Neuropsychiatric Research Program at Cambridge Health Alliance, Cambridge, Massachusetts, where she is also Codirector of the Center for Child and Adolescent Development, and is Associate Professor of Psychiatry at Harvard Medical School, Boston, Massachusetts.

Mary A. Fristad, PhD, is Professor of Psychiatry and Psychology at The Ohio State University (OSU), and Director of Research and Psychological Services in the OSU Division of Child and Adolescent Psychiatry, Columbus, Ohio.

Barbara Geller, MD, is Professor of Psychiatry at Washington University School of Medicine in St. Louis.

Martin Gignac, MD, FRCP, is a psychiatrist and clinical research coordinator at the adolescents' unit of the Institut Philippe-Pinel de Montréal, Montréal, Québec, Canada.

Joseph A. Jackson, DO, is Instructor in Psychiatry at Harvard Medical School and is Medical Director of the Developmental Disabilities Program at the Center for Child and Adolescent Development, Cambridge Health Alliance, Cambridge, Massachusetts.

Gagan Joshi, MD, is Scientific Director of the Pervasive Developmental Disorders Research Program in the Pediatric Psychopharmacology Unit at the Massachusetts General Hospital, and Instructor in Psychiatry at Harvard Medical School, Boston, Massachusetts.

Paramjit T. Joshi, MD, is Endowed Chair of the Department of Psychiatry and Behavioral Sciences at the Children's National Medical Center, and Professor of Psychiatry, Behavioral Sciences and Pediatrics at the George Washington University School of Medicine, Washington, DC.

Robert A. Kowatch, MD, is Professor of Psychiatry and Pediatrics at Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Joan L. Luby, MD, is Associate Professor of Child Psychiatry and founder and director of the Early Emotional Development Program at the Washington University School of Medicine in St. Louis, St. Louis, Missouri.

Molly McGrath, LCSW, is a research clinician with the Early Emotional Development Program at Washington University School of Medicine in St. Louis, St. Louis, Missouri.

David J. Miklowitz, PhD, is Professor of Psychology and Psychiatry at the University of Colorado, Boulder, Colorado, and a senior clinical Research Fellow in the Department of Psychiatry at Oxford University, Oxford, United Kingdom.

Kimberley L. Mullen, MA, is a doctoral candidate in clinical psychology at the University of Colorado, Boulder, Colorado.

Nick C. Patel, PharmD, PhD, is Assistant Professor of Pharmacy at the University of Georgia, Athens, Georgia, and Assistant Professor of Psychiatry at the Medical College of Georgia, Augusta, Georgia.

Jennifer Pautsch, MA, is a study coordinator for the Early Intervention in Depression Study and oversees the clinical research mental health assessments in the Early Emotional Development Program at Washington University School of Medicine in St. Louis, St. Louis, Missouri.

Mani N. Pavuluri, MD, PhD, is Associate Professor of Psychiatry and Director of the Pediatric Mood Disorders Program at the University of Illinois at Chicago, Chicago, Illinois.

Mark A. Riddle, MD, is Professor of Psychiatry and Pediatrics and Director of the Division of Child and Adolescent Psychiatry at the Johns Hopkins University School of Medicine, Baltimore, Maryland. He also serves as Vice President for Psychiatric Sciences at the Kennedy Krieger Institute.

Adelaide S. Robb, MD, is Associate Professor of Psychiatry and Pediatrics at the Children's National Medical Center, Washington, DC, where she is Medical Director of Inpatient Psychiatry.

Russell E. Scheffer, MD, is Professor and Chair of the Department of Psychiatry and Behavioral Sciences and Professor of Pediatrics at the Kansas University Medical Center-Wichita, Wichita, Kansas.

Melissa Meade Stalets, MA, is an infant mental health specialist for an early intervention program in Illinois, and formerly was a researcher in the Early Emotional Development Program at the Washington University School of Medicine in St. Louis, St. Louis, Missouri.

Rebecca Tillman, MS, is a senior statistical data analyst at Washington University School of Medicine in St. Louis, St. Louis, Missouri.

Benedetto Vitiello, MD, is Chief of the Child and Adolescent Treatment and Preventive Interventions Research Branch, National Institute of Mental Health, and is Adjunct Professor of Psychiatry at Johns Hopkins University, Baltimore, Maryland.

Karen Dineen Wagner, MD, PhD, is the Marie B. Gale Professor and Vice Chair in the Department of Psychiatry and Behavioral Sciences and Director of the Division of Child and Adolescent Psychiatry at the University of Texas Medical Branch in Galveston, Texas.

John T. Walkup, MD, is Associate Professor of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Johns Hopkins Medical Institutions in Baltimore, Maryland, where he currently serves as Deputy Director of the Division of Child and Adolescent Psychiatry.

Timothy E. Wilens, MD, is Associate Professor of Psychiatry at Harvard Medical School, Boston, Massachusetts, and is Director of Substance Abuse Services in the Clinical and Research Program in Pediatric Psychopharmacology at Massachusetts General Hospital.

Janet Wozniak, MD, is Director of the Pediatric Bipolar Disorder Research Program in the Pediatric Psychopharmacology Unit at the Massachusetts General Hospital, and Assistant Professor of Psychiatry at Harvard Medical School, Boston, Massachusetts.

Audience

Child/adolescent psychiatrists, clinical psychologists, and other health care professionals treating this population; researchers, students, and residents.

Course Use

May serve as a text in psychiatric residency programs.