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“A detailed and information-packed volume that provides up-to-date knowledge about varieties of bipolar disorder (BD) and the difficulties and frustrations in diagnosis and treatment. The contributors are experts in the etiology, diagnosis, and treatment of bipolar disorders, and each chapter addresses issues in BD such as genetics, neurological changes, age-of-onset differences, pharmacological choices, and treatments, as well as a brief summary of findings....This volume can best be used as a reference text and resource for clinicians seeking a more nuanced understanding of what families are coping with while caring for a BD family member; what BD patients are feeling and how their behaviors affect family functioning; and how families support or inhibit a patient's ability to control emotions and difficult or life-threatening behaviors. Clinicians themselves may experience frustration working with youths with BD because cycles and relapses are so prevalent. The information in this volume can provide them with more tools as well as increase their sense of empathy for families facing the daily stresses of coping with a family member with BD and can provide more tools.”

—PsycCRITIQUES


“This work is useful and progressive, incorporating views and perspectives from leading experts. It is an excellent source of references that summarize recent advances in early intervention and treatment, in addition to contextualizing issues from a historical perspective....This book is recommended to any researcher, clinician, or student who wishes to gain a better understanding of the developmental processes of bipolar disorder.”

—Child and Adolescent Mental Health Journal


“This scholarly work is a tour de force of bipolar disorder across the life-span. Each chapter is a solid review of the literature on different core aspects of the disease from a developmental perspective. The use of language is precise and cogent, while the narrative in this book is compelling. The discussions are thoughtful, conscious of the limitations of current academic knowledge, and future-oriented towards what needs to be unearthed next....One of this work's greatest achievements is that it is comprehensive without losing its depth. This is a significant book for any mental health professional interested in the matters of nature versus nurture across the life span.”

—Journal of the Canadian Academy of Child and Adolescent Psychiatry


“Finally! For the first time, this important book has placed bipolar disorder in a lifespan developmental context—something the field has sorely needed. Understanding Bipolar Disorder is a major contribution. Miklowitz and Cicchetti have produced an indispensable and comprehensive guide to the developmental aspects of the disorder, integrating cutting-edge neuroscience, clinical research, epidemiology, and therapeutics. They have assembled leaders in the field to produce a scholarly, accessible work that will be essential reading for clinicians, researchers, and trainees for years to come.”

—Jordan W. Smoller, MD, ScD, Department of Psychiatry, Harvard Medical School and Massachusetts General Hospital


“This volume approaches bipolar disorder from many different angles, all through the lens of developmental psychopathology. It gives the reader a unique perspective on emerging data on the genetics and neurobiology of the disorder, its etiology, and psychotherapeutic and pharmacological treatments. Miklowitz and Cicchetti have provided an important resource for psychology and psychiatry trainees as well as more experienced clinicians who are confronting this very real public health issue.”

—Kiki D. Chang, MD, Director, Pediatric Bipolar Disorders Program, Stanford University School of Medicine, Lucile Packard Children's Hospital


“This book is a 'must' for anyone interested in a developmental perspective on bipolar disorder across the lifespan. It is likely to become the standard reference in the area. Miklowitz and Cicchetti have chosen their contributors well, producing a volume of great value and one that fills an important void in the literature.”

—Ellen Frank, PhD, Distinguished Professor of Psychiatry and Professor of Psychology, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine


“A tour de force. This book masterfully brings together all that is known about the biological, social, and psychological factors that contribute to bipolar disorder and that underlie treatment. In chapter after chapter, internationally acclaimed authors present their areas of expertise with extraordinary breadth and depth, and with great compassion for people with the disorder. Will surely be required reading for researchers, clinicians, and students.”

—Mark Williams, PhD, Wellcome Principal Research Fellow, Department of Psychiatry, University of Oxford, United Kingdom

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Table of Contents

1. A Developmental Psychopathology Perspective on Bipolar Disorder, Dante Cicchetti

I. Phenomenology and Diagnosis

2. Development, Age of Onset, and Phenomenology in Bipolar Disorder, Stephanie E. Meyer and Gabrielle A. Carlson

3. A Developmental Psychopathology Perspective on the Assessment and Diagnosis of Bipolar Disorder, Eric A. Youngstrom

4. Bipolar Disorder in the Preschool Period: Development and Differential Diagnosis, Joan L. Luby, Andy C. Belden, and Mini Tandon

II. Onset, Prognosis, and Course

5. Clinical Presentation and Longitudinal Course of Bipolar Spectrum Disorders in Children and Adolescents, Rasim Somer Diler, Boris Birmaher, & David J. Miklowitz

6. Course of Early-Onset Bipolar Spectrum Disorders during the College Years: A Behavioral Approach System Dysregulation Perspective, Lauren B. Alloy, Lyn Y. Abramson, Snezana Urosevic, Robin Nusslock, and Shari Jager-Hyman

7. A Developmental Perspective on the Course of Bipolar Disorder in Adulthood, Joseph F. Goldberg

III. Etiology/Risk and Protective Mechanisms

8. Genetic and Environmental Vulnerability to Bipolar Spectrum Disorders, Erik Willcutt and Matthew McQueen

9. Neurodevelopment in Bipolar Disorder: A Neuroimaging Perspective, David E. Fleck, Michael A. Cerullo, Jayasree Nandagopal, Caleb M. Adler, Nick C. Patel, Stephen M. Strakowski, and Melissa P. DelBello

10. Adolescent-Onset Bipolar Spectrum Disorders: A Cognitive Vulnerability–Stress Perspective, Lauren B. Alloy, Lyn Y. Abramson, Patricia D. Walshaw, Jessica Keyser, and Rachel K. Gerstein

11. Social Cognition and Cognitive Flexibility in Bipolar Disorder, Erin B. McClure-Tone

12. The Role of Stress in the Onset, Course, and Progression of Bipolar Illness and Its Comorbidities: Implications for Therapeutics, Robert M. Post and David J. Miklowitz

IV. Treatment

13. Developmental Considerations in the Pharmacological Treatment of Youth with Bipolar Disorder, Robert A. Kowatch, Jeffrey R. Strawn, and Melissa P. DelBello

14. Pharmacotherapy for Adults with Bipolar Depression

Michael E. Thase

15. Family-Based Approaches to Treating Bipolar Disorder in Adolescence: Family-Focused Therapy and Dialectical Behavior Therapy

David J. Miklowitz & Tina R. Goldstein

16. Psychoeducational Psychotherapy for Children with Bipolar Disorder

Amy N. Mendenall and Mary A. Fristad

V. A First-Person Account

17. Growin Up in a Family with Bipolar Disorder: Personal Experience, Developmental Issues, and Overcoming Stigma

Stephen P. Hinshaw

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About the Editors

David J. Miklowitz, PhD, is Distinguished Professor of Psychiatry and Biobehavioral Sciences at the Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, and Visiting Professor in the Department of Psychiatry at the University of Oxford, United Kingdom. He is author of The Bipolar Disorder Survival Guide and Living Well with Bipolar Disorder, for general readers, and several award-winning books for professionals, including Bipolar Disorder: A Family-Focused Treatment Approach. Dr. Miklowitz has published over 300 scientific articles and 70 book chapters. He has won Distinguished Investigator awards from the Brain and Behavior Research Foundation, the Depression and Bipolar Support Alliance, the International Society for Bipolar Disorders, and the Society for a Science of Clinical Psychology. Dr. Miklowitz is one of the few psychologists to have received the Award for Research in Mood Disorders from the American College of Psychiatrists.

• Author's website
• All titles by David J. Miklowitz

Dante Cicchetti, PhD, is McKnight Presidential Chair and Professor of Child Psychology and Psychiatry at the University of Minnesota. His research focuses on developmental theory as well as science, policy, and practice related to child maltreatment, depression, mental retardation, and other domains of development. Dr. Cicchetti has received awards including the three highest honors of the Developmental Division of the American Psychological Association: the G. Stanley Hall Award for Distinguished Contribution to Developmental Psychology, the Urie Bronfenbrenner Award for Lifetime Contribution to Developmental Psychology in the Service of Science and Society, and the Mentor Award in Developmental Psychology. He has published over 400 articles, books, and journal special issues, and is the founding and current Editor of Development and Psychopathology.

• Author's website

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Contributors

Lyn Y. Abramson, PhD, Department of Psychology, University of Wisconsin, Madison, Wisconsin

Caleb M. Adler, MD, Center for Imaging Research and Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio

Lauren B. Alloy, PhD, Department of Psychology, Temple University, Philadelphia, Pennsylvania

Andy C. Belden, PhD, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri

Boris Birmaher, MD, Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Gabrielle A. Carlson, PhD, Department of Child and Adolescent Psychiatry, Stony Brook University School of Medicine, Stony Brook, New York

Michael A. Cerullo, MD, Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio

Dante Cicchetti, PhD, Institute of Child Development and Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota

Melissa P. DelBello, MD, Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio

Rasim Somer Diler, MD, Department of Child and Adolescent Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

David E. Fleck, PhD, Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio

Mary A. Fristad, PhD, ABPP, Departments of Psychiatry and Psychology, Ohio State University Medical Center, Columbus, Ohio

Rachel K. Gerstein, MA, Department of Psychology, Temple University, Philadelphia, Pennsylvania

Joseph F. Goldberg, MD, Affective Disorders Research Program, Silver Hill Hospital, New Canaan, Connecticut

Tina R. Goldstein, PhD, Department of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Stephen P. Hinshaw, PhD, Department of Psychology, University of California Berkeley, Berkeley, California

Shari Jager-Hyman, MA, Department of Psychology, Temple University, Philadelphia, Pennsylvania

Jessica Keyser, MA, Department of Psychology, Temple University, Philadelphia, Pennsylvania

Robert A. Kowatch, MD, PhD, Division of Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Joan L. Luby, MD, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri

Erin B. McClure-Tone, PhD, Department of Psychology, Georgia State University, Atlanta, Georgia

Matthew McQueen, ScD, Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado

Amy N. Mendenhall, PhD, MSW, School of Social Welfare, University of Kansas, Lawrence, Kansas

Stephanie E. Meyer, PhD, Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Neurosciences, Cedars Sinai Medical Center, Los Angeles, California

David J. Miklowitz, PhD, University of California, Los Angeles Semel Institute, David Geffen School of Medicine, and Department of Psychiatry, Oxford University, United Kingdom;

Jayasree Nandagopal, MD, Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio

Robin Nusslock, PhD, Department of Psychology, Northwestern University, Evanston, Illinois

Nick C. Patel, PharmD, PhD, Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta, Georgia; Corphealth Incorporated, Fort Worth, Texas

Robert M. Post, MD, Department of Psychiatry, George Washington University School of Medicine, Washington, DC; Bipolar Collaborative Network, Bethesda, Maryland

Stephen M. Strakowski, MD, Center for Imaging Research and Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio

Jeffrey R. Strawn, MD, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio

Mini Tandon, DO, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri

Michael E. Thase, MD, Department of Psychiatry, University of Pennsylvania School of Medicine and Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania; Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Snezana Urosevic, PhD, Department of Psychology, University of Wisconsin, Madison, Wisconsin

Patricia D. Walshaw, PhD, Department of Psychiatry and Biobehavioral Science, University of California Los Angeles, Los Angeles, California

Erik Willcutt, PhD, Institute for Behavioral Genetics and Department of Psychology and Neuroscience, University of Colorado, Boulder, Colorado

Eric A. Youngstrom, PhD, Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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Audience

Adult and child clinical psychologists, psychiatrists, developmental psychologists, clinical social workers; researchers and graduate students across the mental health disciplines.

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Course Use

May serve as a supplemental text in graduate-level courses.