From foundational concepts to emerging technologies, this book reviews current human neuroplasticity research and its clinical applications. Experts in the field cover the biology and mechanisms of neuronal plasticity, its role in learning and development, and cortical reorganization in aging and disease. Chapters explore the challenges of translating research into effective, individualized treatments for neurological and psychiatric conditions across the lifespan. Cutting-edge topics include enhancing brain health in older adults, advances in brain–computer interfaces, and the impact of intensive digital media use on cognition, attention, and brain organization.